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Journal of Attention Disorders Review. It is possible that in untreated patients with CD, neurologic symptoms such as chronic fatigue, inattention, pain, and headache could predispose patients to ADHD-like behavior mainly symptoms of inattentive type , which may be alleviated after GFD treatment.

Frontiers in Psychology. Psychological Assessment. Journal of Child Psychology and Psychiatry. Abnormal Psychology Sixth ed.

Annual Review of Clinical Psychology. Human Genetics. European Archives of Psychiatry and Clinical Neuroscience.

Reviews on Recent Clinical Trials. Molecular Pharmacology. Social Cognitive and Affective Neuroscience. Journal of the Royal Society Interface.

Stanford, Clare. Heidelberg: Springer-Verlag Berlin Heidelberg. The American Journal of Psychiatry.

Free fatty acid supplementation and artificial food color exclusions appear to have beneficial effects on ADHD symptoms, although the effect of the former are small and those of the latter may be limited to ADHD patients with food sensitivities Fortschritte der Neurologie-Psychiatrie Review in German.

Environmental Health Perspectives Review. Research Support, N. Research Support, U. Gov't, Non-P. Acta Paediatrica Review. Research Support, Non-U.

Critical Reviews in Toxicology Review. Archives of Disease in Childhood Review. Pediatrics Review. Expert Review of Neurotherapeutics Review.

Harvard University Press. Archived from the original on 11 September Encyclopedia of Food Safety. Very few studies enable proper evaluation of the likelihood of response in children with ADHD who are not already preselected based on prior diet response.

Disorders of Childhood: Development and Psychopathology. Cengage Learning. Retrieved 6 July Year Book of Pediatrics E-Book.

Elsevier Health Sciences. Archived from the original PDF on 24 October Retrieved 13 October Child and Adolescent Psychiatry and Mental Health. Pharmacracy: medicine and politics in America.

Westport, CT: Praeger. Mental diseases are invented and then given a name, for example attention deficit hyperactivity disorder ADHD.

Frontiers in Neural Circuits. Early results with structural MRI show thinning of the cerebral cortex in ADHD subjects compared with age-matched controls in prefrontal cortex and posterior parietal cortex, areas involved in working memory and attention.

DA has multiple actions in the prefrontal cortex. It promotes the "cognitive control" of behavior: the selection and successful monitoring of behavior to facilitate attainment of chosen goals.

Aspects of cognitive control in which DA plays a role include working memory, the ability to hold information "on line" in order to guide actions, suppression of prepotent behaviors that compete with goal-directed actions, and control of attention and thus the ability to overcome distractions.

Cognitive control is impaired in several disorders, including attention deficit hyperactivity disorder.

Noradrenergic projections from the LC thus interact with dopaminergic projections from the VTA to regulate cognitive control. Trends in Cognitive Sciences.

Recent conceptualizations of ADHD have taken seriously the distributed nature of neuronal processing [10,11,35,36]. Most of the candidate networks have focused on prefrontal-striatal-cerebellar circuits, although other posterior regions are also being proposed [10].

Clinical Psychology Review. April The Lancet. A meta-analysis". Pharmacology, Biochemistry, and Behavior. European Journal of Paediatric Neurology.

European Neuropsychopharmacology. Annual Review of Psychology. EFs and prefrontal cortex are the first to suffer, and suffer disproportionately, if something is not right in your life.

They suffer first, and most, if you are stressed Arnsten , Liston et al. A review of the literature".

Behavioral studies show altered processing of reinforcement and incentives in children with ADHD. These children respond more impulsively to rewards and choose small, immediate rewards over larger, delayed incentives.

Interestingly, a high intensity of reinforcement is effective in improving task performance in children with ADHD. Pharmacotherapy may also improve task persistence in these children.

Previous studies suggest that a clinical approach using interventions to improve motivational processes in patients with ADHD may improve outcomes as children with ADHD transition into adolescence and adulthood.

August Archived from the original on 1 May Textbook Of Child and Adolescent Psychiatry illustrated ed. Archived from the original on 6 May Retrieved 2 November Tidsskrift for den Norske Laegeforening in Norwegian.

Clinical EEG and Neuroscience. United States Food and Drug Administration. Archived from the original on 25 September Psychiatry Research.

Assessment of Childhood Disorders 4th ed. Frontiers in Psychiatry. The Israel Medical Association Journal.

Retrieved 23 June Best Buy Drugs : 2. Archived PDF from the original on 15 November Retrieved 12 April Journal of Clinical Sleep Medicine.

Retrieved 13 March Conversely, methylphenidate, …showed poor efficacy at the TAAR1 receptor. In this respect it is worth noting that the enhancement of functioning at TAAR1 seen with modafanil was not a result of a direct interaction with TAAR1.

Saudi Pharmaceutical Journal. BMC Medicine. The Psychiatric Clinics of North America. Cochrane Database of Systematic Reviews.

Journal of Clinical Child and Adolescent Psychology. Archived from the original PDF on 4 April Retrieved 21 November Bjornstad GJ ed.

The Encyclopedia of the Brain and Brain Disorders. Infobase Publishing. Clinical Child and Family Psychology Review.

The effects of physical exercise on cognition and behavior in children and adults with ADHD: a systematic literature review". Journal of Neural Transmission.

Beneficial chronic effects of cardio exercise were found on various functions as well, including executive functions, attention and behavior.

Acta Paediatrica. We may conclude that all different types of exercise The findings from these studies provide some support for the notion that exercise has the potential to act as a protective factor for ADHD.

Drugs of Today. Drug Class Reviews. United States Library of Medicine. Archived from the original on 31 August A systematic review and meta-analysis".

In addition, a consensus has not been reached on the optimal diagnostic criteria for ADHD. Moreover, the benefits and long-term effects of medical and complementary therapies for this disorder continue to be debated.

These gaps in knowledge hinder the ability of clinicians to effectively recognize and treat ADHD. JAMA Psychiatry. The Journal of Clinical Psychiatry.

Acta Psychiatrica Scandinavica. Basal ganglia regions like the right globus pallidus, the right putamen, and the nucleus caudatus are structurally affected in children with ADHD.

These changes and alterations in limbic regions like ACC and amygdala are more pronounced in non-treated populations and seem to diminish over time from child to adulthood.

Treatment seems to have positive effects on brain structure. Archived from the original on 8 May Retrieved 19 June Archived from the original on 7 December As most treatment guidelines and prescribing information for stimulant medications relate to experience in school-aged children, prescribed doses for older patients are lacking.

Emerging evidence for both methylphenidate and Adderall indicate that when weight-corrected daily doses, equipotent with those used in the treatment of younger patients, are used to treat adults with ADHD, these patients show a very robust clinical response consistent with that observed in pediatric studies.

These data suggest that older patients may require a more aggressive approach in terms of dosing, based on the same target dosage ranges that have already been established — for methylphenidate, 1—1.

In particular, adolescents and adults are vulnerable to underdosing, and are thus at potential risk of failing to receive adequate dosage levels.

As with all therapeutic agents, the efficacy and safety of stimulant medications should always guide prescribing behavior: careful dosage titration of the selected stimulant product should help to ensure that each patient with ADHD receives an adequate dose, so that the clinical benefits of therapy can be fully attained.

Southern Medical Journal. Shoptaw SJ, Ali R ed. A minority of individuals who use amphetamines develop full-blown psychosis requiring care at emergency departments or psychiatric hospitals.

In such cases, symptoms of amphetamine psychosis commonly include paranoid and persecutory delusions as well as auditory and visual hallucinations in the presence of extreme agitation.

Findings from one trial indicate use of antipsychotic medications effectively resolves symptoms of acute amphetamine psychosis.

Shire US Inc. December Archived PDF from the original on 30 December Retrieved 30 December Treatment-emergent psychotic or manic symptoms, e.

In a pooled analysis of multiple short-term, placebo controlled studies, such symptoms occurred in about 0. Clinical Neuropharmacology.

How long should medication treatment of attention-deficit hyperactivity disorder be extended? Archived PDF from the original on 30 June Sydor A, Brown RY eds.

Second, untreated ADHD may lead to school failure, peer rejection, and subsequent association with deviant peer groups that encourage drug misuse.

Archived from the original on 8 September Journal of Psychopharmacology. Journal of Child and Adolescent Psychopharmacology. Several studies e.

Roczniki Panstwowego Zakladu Higieny. Expert Review of Neurotherapeutics. Zinc binds at In this context, controlled double-blind studies in children are of interest, which showed positive effects of zinc [supplementation] on symptoms of ADHD [,].

It should be stated that at this time [supplementation] with zinc is not integrated in any ADHD treatment algorithm.

Neuropsychiatric Disease and Treatment. Disease Primers Review. Annals of the New York Academy of Sciences. Retrieved 31 March Center For Disease Control and Prevention.

Archived PDF from the original on 7 August Retrieved 2 August Psychiatric Times. Child and Adolescent Mental Health.

An inquiry into the nature and origin of mental derangement: comprehending a concise system of the physiology and pathology of the human mind and a history of the passions and their effects.

Retrieved 17 January — via Google Books. Lancet : — Deviant Behavior. Mental Deficiency Amentia 1 ed. Journal of Attention Disorders : — Springer Science.

Journal of the History of Medicine and Allied Sciences. Human Psychopharmacology. American Journal of Psychiatry : New York: Guilford.

Archives of Disease in Childhood. The Guardian. Archived from the original on 8 July Journal of Pediatric Nursing.

The New York Times 14 December Retrieved 26 February Journal of Health Economics. Alan Schwarz Attention deficit hyperactivity disorder.

Deferred gratification Auditory processing disorder Deficits in attention, motor control and perception Developmental coordination disorder Low arousal theory Sluggish cognitive tempo Sensory processing disorder Hunter vs.

ADHD pharmacotherapies. Amphetamine Mixed amphetamine salts , Levoamphetamine , Dextroamphetamine , Lisdexamfetamine Methamphetamine Methylphenidate Dexmethylphenidate.

Armodafinil Atomoxetine Modafinil. Clonidine Guanfacine. Amantadine Carbamazepine. Dexedrine ProCentra Zenzedi. Emotional and behavioral disorders.

Mental and behavioral disorders. Adult personality and behavior. Ego-dystonic sexual orientation Paraphilia Fetishism Voyeurism Sexual maturation disorder Sexual relationship disorder.

Factitious disorder Munchausen syndrome Intermittent explosive disorder Dermatillomania Kleptomania Pyromania Trichotillomania Personality disorder.

Childhood and learning. X-linked intellectual disability Lujan—Fryns syndrome. Pervasive Specific. Mood affective. Neurological and symptomatic.

Delirium Organic brain syndrome Post-concussion syndrome. Neurotic , stress -related and somatoform. Adjustment disorder with depressed mood.

Depersonalization disorder Dissociative identity disorder Fugue state Psychogenic amnesia. Body dysmorphic disorder Conversion disorder Ganser syndrome Globus pharyngis Psychogenic non-epileptic seizures False pregnancy Hypochondriasis Mass psychogenic illness Nosophobia Psychogenic pain Somatization disorder.

Physiological and physical behavior. Anorexia nervosa Bulimia nervosa Rumination syndrome Other specified feeding or eating disorder. Postpartum depression Postpartum psychosis.

Erectile dysfunction Female sexual arousal disorder. Hypersexuality Hypoactive sexual desire disorder. Anorgasmia Delayed ejaculation Premature ejaculation Sexual anhedonia.

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Associated conditions that should be screened for include anxiety, depression, oppositional defiant disorder, conduct disorder, and learning and language disorders.

Other conditions that should be considered are other neurodevelopmental disorders, tics , and sleep apnea. As with many other psychiatric disorders, formal diagnosis should be made by a qualified professional based on a set number of criteria.

This subdivision is based on presence of at least six out of nine long-term lasting at least six months symptoms of inattention, hyperactivity—impulsivity, or both.

When a conduct disorder as defined by ICD [61] is present, the condition is referred to as hyperkinetic conduct disorder. Otherwise, the disorder is classified as disturbance of activity and attention , other hyperkinetic disorders or hyperkinetic disorders, unspecified.

The latter is sometimes referred to as hyperkinetic syndrome. In the implementation version of ICD , the disorder is classified under 6A05 Attention deficit hyperactivity disorder and hyperkinetic disorder no longer exists.

Adults with ADHD are diagnosed under the same criteria, including that their signs must have been present by the age of six to twelve.

Questioning parents or guardians as to how the person behaved and developed as a child may form part of the assessment; a family history of ADHD also adds weight to a diagnosis.

Some ADHD symptoms in adults differ from those seen in children. While children with ADHD may climb and run about excessively, adults may experience an inability to relax, or they talk excessively in social situations.

Adults with ADHD may start relationships impulsively, display sensation-seeking behavior, and be short-tempered.

Addictive behavior such as substance abuse and gambling are common. The DSM-V criteria do specifically deal with adults, unlike those in DSM-IV, which were criticized for not being appropriate for adults; those who presented differently may lead to the claim that they outgrew the diagnosis.

Symptoms of ADHD, such as low mood and poor self-image, mood swings, and irritability, can be confused with dysthymia , cyclothymia or bipolar disorder as well as with borderline personality disorder.

These disorders can also sometimes occur along with ADHD. Medical conditions which can cause ADHD type symptoms include: hyperthyroidism , seizure disorder , lead toxicity , hearing deficits , hepatic disease , sleep apnea , drug interactions , untreated celiac disease , and head injury.

Primary sleep disorders may affect attention and behavior and the symptoms of ADHD may affect sleep. Reviews of ADHD biomarkers have noted that platelet monoamine oxidase expression, urinary norepinephrine , urinary MHPG , and urinary phenethylamine levels consistently differ between ADHD individuals and healthy control.

The management of ADHD typically involves counseling or medications either alone or in combination. While treatment may improve long-term outcomes, it does not get rid of negative outcomes entirely.

There is good evidence for the use of behavioral therapies in ADHD and they are the recommended first line treatment in those who have mild symptoms or are preschool-aged.

There is little high quality research on the effectiveness of family therapy for ADHD, but the evidence that exists shows that it is similar to community care and better than a placebo.

Training in social skills, behavioral modification and medication may have some limited beneficial effects. The most important factor in reducing later psychological problems, such as major depression , criminality , school failure, and substance use disorders is formation of friendships with people who are not involved in delinquent activities.

Regular physical exercise , particularly aerobic exercise , is an effective add-on treatment for ADHD in children and adults, particularly when combined with stimulant medication, although the best intensity and type of aerobic exercise for improving symptoms are not currently known.

Stimulant medications are the pharmaceutical treatment of choice. There are a number of non-stimulant medications, such as atomoxetine , bupropion , guanfacine , and clonidine that may be used as alternatives, or added to stimulant therapy.

Guidelines on when to use medications vary by country. However, most United States guidelines recommend medications in most age groups.

While stimulants and atomoxetine are usually safe, there are side-effects and contraindications to their use. Dietary modifications are not recommended as of by the American Academy of Pediatrics due to insufficient evidence.

But executive function deficits have a limited response to ADHD medications. Rates of diagnosis and treatment have increased in both the United Kingdom and the United States since the s.

Hyperactivity has long been part of the human condition. Sir Alexander Crichton describes "mental restlessness" in his book An inquiry into the nature and origin of mental derangement written in Alfred Tredgold proposed an association between brain damage and behavioral or learning problems which was able to be validated by the encephalitis lethargica epidemic from through In , Benzedrine became the first amphetamine medication approved for use in the United States.

Until the s, many studies "implicated the prefrontal-striatal network as being smaller in children with ADHD".

ADHD, its diagnosis, and its treatment have been controversial since the s. With widely differing rates of diagnosis across countries, states within countries, races, and ethnicities, some suspect factors other than the presence of the symptoms of ADHD are playing a role in diagnosis.

Quotations related to Attention deficit hyperactivity disorder at Wikiquote. From Wikipedia, the free encyclopedia. Redirected from ADHD.

Neurodevelopmental disorder marked by difficulty focusing, or excessive activity and impulsive behavior. See also: Diet and attention deficit hyperactivity disorder.

Main article: Adult attention deficit hyperactivity disorder. Main article: Attention deficit hyperactivity disorder management.

Main article: Diet and attention deficit hyperactivity disorder. Main article: Epidemiology of attention deficit hyperactive disorder.

Main article: History of attention deficit hyperactivity disorder. Main article: Attention deficit hyperactivity disorder controversies. National Institute of Mental Health.

March Archived from the original on 23 July Retrieved 5 March Diagnostic and Statistical Manual of Mental Disorders 5th ed. Arlington: American Psychiatric Publishing.

Archived from the original on 7 November Retrieved 3 November Archived from the original on 14 April Retrieved 17 April February European Psychiatry.

Chapter A. American Journal of Pediatrics. Retrieved 22 May Neuroscience Bulletin. Encyclopedia of Cross-Cultural School Psychology.

Journal of Abnormal Child Psychology. Neuroscience and Biobehavioral Reviews. Concise Guide to Child and Adolescent Psychiatry 4th illustrated ed.

American Psychiatric Publishing. Therapeutische Umschau in German. Nature Genetics. Retrieved 27 August Twin studies also suggest that diagnosed ADHD represents the extreme tail of one or more heritable quantitative traits.

Shorter Oxford Textbook of Psychiatry 6th ed. Oxford University Press. Textbook of Psychiatric Epidemiology 3rd ed. Monitor on Psychology.

Archived from the original on 9 April L'Encephale in French. Nature Reviews. BMC Psychiatry. Psychiatria Hungarica in Hungarian.

Reports indicate that ADHD affects 2. Leicester: British Psychological Society. Retrieved 4 February Centers for Disease Control and Prevention.

Archived from the original on 7 July Retrieved 13 July October The Cochrane Database of Systematic Reviews.

Retrieved 1 January Why were the MTA medication treatments more effective than community treatments that also usually included medication?

Answer: There were substantial differences in quality and intensity between the study-provided medication treatments and those provided in the community care group.

CNS Drugs. Bibcode : PLoSO.. Psychology Research and Behavior Management. Results suggest there is moderate-to-high-level evidence that combined pharmacological and behavioral interventions, and pharmacological interventions alone can be effective in managing the core ADHD symptoms and academic performance at 14 months.

However, the effect size may decrease beyond this period. Only one paper examining outcomes beyond 36 months met the review criteria.

Attention Deficit and Hyperactivity Disorders. Encyclopedia of Social Problems. Retrieved 2 May Harvard Review of Psychiatry.

Australian Family Physician. Archived PDF from the original on 24 September Current Opinion in Pediatrics. Amsterdam: Elsevier Academic Press. Archived from the original on 20 April Centers for Disease Control and Prevention Archived from the original on 1 March Retrieved 10 October Cognitive behavioral therapy for adult ADHD.

National Institutes of Health. Archived from the original on 19 January Journal of Attention Disorders. Adolescent Medicine. Archived from the original on 5 November Retrieved 17 January Journal of Child Neurology.

Epidemiology and Psychiatric Sciences. Retrieved 15 May Postgraduate Medicine. There is a way". Archived from the original on 3 December Retrieved 15 November Current Opinion in Psychiatry.

Pediatric Clinics of North America. The Medical Clinics of North America. Current Psychiatry Reports. The Annals of Pharmacotherapy. Wolters Kluwer Health.

Archived from the original on 5 June Retrieved 12 September International Journal of Law and Psychiatry.

Biological Psychiatry. The Journal of Pediatrics. Archived PDF from the original on 9 August Sleep Medicine. Revue Neurologique in French.

Journal of Attention Disorders Systematic Review. A Systematic Review of the Literature". Journal of Attention Disorders Review.

It is possible that in untreated patients with CD, neurologic symptoms such as chronic fatigue, inattention, pain, and headache could predispose patients to ADHD-like behavior mainly symptoms of inattentive type , which may be alleviated after GFD treatment.

Frontiers in Psychology. Psychological Assessment. Journal of Child Psychology and Psychiatry. Abnormal Psychology Sixth ed. Annual Review of Clinical Psychology.

Human Genetics. European Archives of Psychiatry and Clinical Neuroscience. Reviews on Recent Clinical Trials.

Molecular Pharmacology. Social Cognitive and Affective Neuroscience. Journal of the Royal Society Interface. Stanford, Clare.

Heidelberg: Springer-Verlag Berlin Heidelberg. The American Journal of Psychiatry. Free fatty acid supplementation and artificial food color exclusions appear to have beneficial effects on ADHD symptoms, although the effect of the former are small and those of the latter may be limited to ADHD patients with food sensitivities Fortschritte der Neurologie-Psychiatrie Review in German.

Environmental Health Perspectives Review. Research Support, N. Research Support, U. Gov't, Non-P. Acta Paediatrica Review. Research Support, Non-U.

Critical Reviews in Toxicology Review. Archives of Disease in Childhood Review. Pediatrics Review. Expert Review of Neurotherapeutics Review.

Harvard University Press. Archived from the original on 11 September Encyclopedia of Food Safety. Very few studies enable proper evaluation of the likelihood of response in children with ADHD who are not already preselected based on prior diet response.

Disorders of Childhood: Development and Psychopathology. Cengage Learning. Retrieved 6 July Year Book of Pediatrics E-Book.

Elsevier Health Sciences. Archived from the original PDF on 24 October Retrieved 13 October Child and Adolescent Psychiatry and Mental Health.

Pharmacracy: medicine and politics in America. Westport, CT: Praeger. Mental diseases are invented and then given a name, for example attention deficit hyperactivity disorder ADHD.

Frontiers in Neural Circuits. Early results with structural MRI show thinning of the cerebral cortex in ADHD subjects compared with age-matched controls in prefrontal cortex and posterior parietal cortex, areas involved in working memory and attention.

DA has multiple actions in the prefrontal cortex. It promotes the "cognitive control" of behavior: the selection and successful monitoring of behavior to facilitate attainment of chosen goals.

Aspects of cognitive control in which DA plays a role include working memory, the ability to hold information "on line" in order to guide actions, suppression of prepotent behaviors that compete with goal-directed actions, and control of attention and thus the ability to overcome distractions.

Cognitive control is impaired in several disorders, including attention deficit hyperactivity disorder. Noradrenergic projections from the LC thus interact with dopaminergic projections from the VTA to regulate cognitive control.

Trends in Cognitive Sciences. Recent conceptualizations of ADHD have taken seriously the distributed nature of neuronal processing [10,11,35,36].

Most of the candidate networks have focused on prefrontal-striatal-cerebellar circuits, although other posterior regions are also being proposed [10].

Clinical Psychology Review. April The Lancet. A meta-analysis". Pharmacology, Biochemistry, and Behavior.

European Journal of Paediatric Neurology. European Neuropsychopharmacology. Annual Review of Psychology. EFs and prefrontal cortex are the first to suffer, and suffer disproportionately, if something is not right in your life.

They suffer first, and most, if you are stressed Arnsten , Liston et al. A review of the literature". Behavioral studies show altered processing of reinforcement and incentives in children with ADHD.

These children respond more impulsively to rewards and choose small, immediate rewards over larger, delayed incentives. Interestingly, a high intensity of reinforcement is effective in improving task performance in children with ADHD.

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